Hydrates Database

The hydrates database contains all pharmaceuticals monographed in the European Pharmacopeia (Pharmacopeia Europa 6.2, 2012) and collates information about known hydrates of these drug substances as well as links where relevant experimental data can be found. If there is no hydrate data under a particular entry then it is because we are not aware that it forms a hydrate - please update us if ay are missing. Note that the database includes reported hydrates even where there is no crystallographic data and so it complements other resources such as the Cambridge Structural Database.

Click on the headings to sort the columns as you wish. If you want to search by stoichiometry or by hydrate type please use the search function on the right or our detailed search interface.

Namesort icon Stoichiometry Crystal Data Neutron Data PXRD data IR data Raman data DSC data TGA data Moisture data
Zuclopenthixol decanoate 2/1
Zopiclone 2/1
Zolpidem tartrate 1/1
Zinc undecylenate
Zinc stearate
Zinc acexamate
Zinc acetate 2/1
Zidovudine
Yohimbine hydrochloride
Xylose
Xylometazoline hydrochloride
Xylitol
Xylazine hydrochloride 1/2
Warfarin sodium
Vinpocetine
Vinorelbine tartrate
Vindesine sulphate 2/1
Vincristine sulphate
Vinblastine sulphate 19/1
Verapamil hydrochloride
Venlafaxine hydrochloride
Vecuronium bromide
Vanillin
Vancomycin hydrochloride suggested
Valproic acid
Valnemulin hydrochloride
Valine
Ursodeoxycholic acid
Urea
Undecylenic acid
Ubidecarenone
Tyrosine
Tylosin tartrate
Tylosin
Tubocurarine chloride 5/1
Tryptophan
Troxerutin
Trospium chloride
Tropisetron hydrochloride
Tropicamide
Trometamol
Trolamine
Trimipramine maleate
Trimethoprim 1/1
Trimethadione
Trimetazidine dihydrochloride
Trihexyphenidyl hydrochloride
Triflusal
Trifluoperazine hydrochloride
Triethyl citrate
Tributyl acetylcitrate
Tribenoside
Triamterene
Triamcinolone hexacetonide
Triamcinolone acetonide 0.4/1
Triamcinolone 1/1
Triacetin
Tretinoin
Trapidil
Tranexamic acid
Trandolapril
Tramadol hydrochloride 1/1
Tosylchloramide sodium
Torasemide 1/1
Tolnaftate
Tolfenamic acid
Tolbutamide
Tobramycin 1/1
Tobramycin 2/1
Tobramycin 3/1
Tioconazole
Tinidazole
Timolol maleate
Tilidine hydrochloride 1/2
Ticlopidine hydrochloride
Ticarcillin sodium 1/1
Tibolone
Tiaprofenic acid
Tiapride hydrochloride
Tianeptine sodium
Tiamulin hydrogen fumarate
Tiamulin
Tiabendazole
Threonine
Thioridazine hydrochloride
Thioridazine
Thiopental sodium
Thiomersal
Thioctic acid
Thiamphenicol
Thiamine nitrate
Thiamine hydrochloride 1/1
Thiamine hydrochloride 1/2
Thiamazole
Theophylline-ethylenediamine
Theophylline 1/1
Theobromine
Tetryzoline hydrochloride
Tetrazepam
Tetracycline hydrochloride
Tetracycline 3/1
Tetracycline 6/1
Tetracaine hydrochloride 1/2
Tetracaine hydrochloride 1/1
Tetracaine hydrochloride 4/1
Testosterone propionate
Testosterone isocaproate
Testosterone enantate
Testosterone decanoate
Testosterone 1/1
Terfenadine
Terconazole
Terbutaline sulphate 1/1
Terbutaline sulphate 1.5/1
Terbutaline sulphate 2.5/1
Terbinafine hydrochloride
Terazosin hydrochloride 2/1
Tenoxicam
Temazepam
Telmisartan
Tartaric acid 1/1 (D)
Tartaric acid 1/1 (DL)
Tartaric acid 1/1 (meso)
Tannic acid
Tamoxifen citrate 1.5/1
Suxibuzone
Suxamethonium chloride
Sumatriptan succinate
Sultamicillin tosilate 2/1
Sultamicillin
Sulpiride
Sulindac
Sulfisomidine
Sulfinpyrazone
Sulfathiazole suggested
Sulfasalazine
Sulfanilamide 1/1 (polymorphic)
Sulfamethoxypyridazine
Sulfamethoxazole 1/2
Sulfamethizole 1/1
Sulfamerazine
Sulfaguanidine 1/1
Sulfafurazole
Sulfadoxine
Sulfadimidine
Sulfadiazine
Sulfacetamide sodium 1/1
Sulbactam sodium
Sufentanil citrate
Sufentanil
Sucrose stearate
Sucrose monopalmitate 2/1
Sucrose 2.5/1
Sucrose 2/1
Succinylsulfathiazole 1/1 (polymorphic)
Streptomycin sulphate
Stavudine 1/3
Squalane
Spironolactone
Spirapril hydrochloride 1/1
Spiramycin
Spectinomycin sulphate 4/1
Spectinomycin dihydrochloride 5/1
Sotalol hydrochloride
Sorbitol 2/3
Sorbic acid
Sodium valproate
Sodium stearate 1/8
Sodium stearate 1/2
Sodium salicylate 6/1
Sodium propyl parahydroxybenzoate
Sodium propionate
Sodium phenylbutyrate
Sodium methyl parahydroxybenzoate
Sodium iodohippurate
Sodium hyaluronate
Sodium glycerophosphate 6/1
Sodium glycerophosphate 5.5/1
Sodium fusidate
Sodium cyclamate
Sodium cromoglicate 6.44/1
Sodium citrate 5/1
Sodium citrate 1/1
Sodium citrate 5.5/1
Sodium citrate 2/1
Sodium caprylate
Sodium calcium edetate 2/1
Sodium benzoate 0.28/1
Sodium aurothiomalate 1/1
Sodium ascorbate
Sodium aminosalicylate 2/1
Sodium amidotrizoate 4/1
Sodium alginate
Sodium alendronate 2/1
Sodium acetate 4/1
Sodium acetate 3/1
Simvastatin
Sertraline hydrochloride 1/1 (suggested)
Sertaconazole nitrate 1/1
Serine 2/1 (DL)
Serine 1/1 (L)
Selegiline hydrochloride
Scopolamine hydrobromide 1.5/1
Scopolamine hydrobromide 1/2
Scopolamine hydrobromide 3/1
Scopolamine butylbromide
Scopolamine suggested
Salmeterol xinafoate
Salicylic acid
Salbutamol sulphate
Salbutamol
Saccharin sodium
Saccharin sodium 2/3
Saccharin
S-lactic acid
Rutoside 3/1
RRR-alpha Tocopheryl hydrogen succinate
RRR-alpha Tocopheryl acetate
RRR-alpha Tocopherol
Roxithromycin
Ropivacaine hydrochloride 1/1
Rocuronium bromide
Ritonavir 3/1
Risperidone
Rilmenidine dihydrogen phosphate
Rifamycin sodium
Rifampicin 5/1
Rifampicin 2/1
Rifampicin 1/1
Rifabutin
Riboflavin sodium phosphate suggested
Riboflavin
Ribavirin
Resorcinol
Reserpine
Repaglinide
Ranitidine hydrochloride
Ramipril 1/1
Racecadotril
Quinine sulphate 8/1
Quinine sulphate 2/1
Quinine hydrochloride 2/1
Quinidine sulphate 2/1
Quinidine sulphate 3.5/1
Pyrrolidone
Pyrimethamine
Pyridoxine hydrochloride
Pyridostigmine bromide
Pyrazinamide
Pyrantel embonate
Pseudoephedrine hydrochloride
Proxyphylline
Protirelin
Propyphenazone
Propylthiouracil
Propylene glycol monostearate
Propylene glycol monolaurate
Propylene glycol dilaurate
Propylene glycol
Propyl parahydroxybenzoate
Propyl gallate 2/1
Propranolol hydrochloride
Propofol
Propantheline bromide
Propafenone hydrochloride
Propacetamol hydrochloride
Promethazine hydrochloride
Promazine hydrochloride
Proline 1/1 (DL)
Proline 1/1 (L)
Proguanil hydrochloride
Progesterone
Prochlorperazine maleate
Procaine hydrochloride
Procaine benzylpenicillin
Procainamide hydrochloride
Probenecid
Primidone
Primaquine diphosphate
Prilocaine hydrochloride
Prilocaine
Prednisone
Prednisolone sodium phosphate
Prednisolone pivalate
Prednisolone acetate
Prednisolone 1.5/1
Prednicarbate
Prazosin hydrochloride 2/1
Praziquantel 1/2
Prazepam
Pravastatin sodium
Potassium sorbate
Potassium sodium tartrate 4/1 (polymorphic)
Potassium hydrogen tartrate
Potassium hydrogen aspartate 2/1
Potassium hydrogen aspartate 1/2
Potassium clavulanate
Potassium citrate 2/1
Potassium citrate 1/1
Potassium acetate 1/2
Potassium acetate 1.5/1
Potassium acetate 3/1
Potassium acetate 2/1
Potassium acetate 1/1
Polymyxin B sulphate
Pivmecillinam hydrochloride
Pivampicillin
Piroxicam 1/1
Piretanide
Pirenzepine dihydrochloride 1/1
Piracetam 1/1
Piracetam 2/1
Piperazine citrate
Piperazine adipate
Piperazine 6/1
Piperacillin sodium 1/1
Piperacillin sodium 2.5/1
Piperacillin 1/1
Pipemidic acid 3/1
Pindolol
Pimozide
Pimobendan 1/1
Pilocarpine nitrate
Pilocarpine hydrochloride
Picotamide 1/1
Phytosterol
Phytomenadione
Physostigmine sulphate
Physostigmine salicylate
Phthalylsulfathiazole
Pholcodine
Phloroglucinol 2/1
Phenytoin sodium 8/1
Phenytoin sodium 4/1
Phenytoin sodium 1/1 (polymorphic)
Phenytoin
Phenylpropanolamine hydrochloride
Phenylmercuric nitrate
Phenylmercuric borate
Phenylmercuric acetate
Phenylephrine hydrochloride
Phenylephrine
Phenylbutazone 1/1
Phenylalanine 1/1
Phentolamine mesilate
Phenoxymethylpenicillin potassium
Phenoxymethylpenicillin
Phenoxyethanol
Phenolsulfonphthalein
Phenolphthalein
Phenobarbital sodium
Phenobarbital 1/2
Phenobarbital 1/1
Pheniramine maleate
Phenazone
Pethidine hydrochloride
Perphenazine
Perindopril tert-butylamine
Pergolide mesilate
Pentoxyverine hydrogen citrate
Pentoxifylline
Pentobarbital sodium
Pentobarbital
Pentazocine hydrochloride 0.23/1
Pentazocine suggested
Pentamidine diisetionate 3/1
Pentamidine diisetionate 2/1
Penicillamine
Penbutolol sulphate
Pefloxacin mesilate 2/1
Paroxetine hydrochloride 1/2
Paracetamol 3/1
Paracetamol 2/1
Paracetamol 1/1
Papaverine hydrochloride
Pantoprazole sodium 1.5/1
Pantoprazole sodium 1/1
Pantoprazole sodium 0.5/1
Pantoprazole sodium 2/1
Pancuronium bromide
Pamidronate disodium 5/1
Pamidronate disodium 4/1
Pamidronate disodium 3/1
Pamidronate disodium 1/1
Palmitic acid
Paclitaxel 2/1
Oxytocin
Oxytetracycline hydrochloride 1/1
Oxytetracycline hydrochloride 2/1
Oxytetracycline hydrochloride 1/2
Oxytetracycline 2/1
Oxymetazoline hydrochloride 1/1
Oxycodone hydrochloride suggested
Oxybutynin hydrochloride
Oxybuprocaine hydrochloride
Oxprenolol hydrochloride
Oxolinic acid
Oxitropium bromide
Oxfendazole
Oxeladin hydrogen citrate
Oxazepam
Oxaliplatin
Oxacillin sodium 1/1
Ouabain 2/1
Ouabain 3/1
Ouabain 4/1
Ouabain 8/1
Ouabain 9/1
Ouabain 10/1
Orphenadrine hydrochloride
Orphenadrine citrate
Orciprenaline sulphate
Ondansetron hydrochloride 2/1
Omeprazole sodium 1/1
Omeprazole
Olsalazine sodium
Oleic acid
Ofloxacin
Octyl gallate 2/1
Nystatin
Noscapine hydrochloride suggested
Noscapine
Nortriptyline hydrochloride
Norgestrel
Norgestimate
Norfloxacin 2/1
Norfloxacin 1.5/1 (polymorphic)
Norfloxacin 1.25/1
Norfloxacin 2.5/1
Norfloxacin 3/1
Norfloxacin 5/1
Norethisterone acetate
Norethisterone
Norepinephrine tartrate suggested
Norepinephrine hydrochloride suggested
Noradrenaline tartrate suggested
Noradrenaline hydrochloride suggested
Nomegestrol acetate
Nizatidine
Nitrofurantoin 1/1 (polymorphic)
Nitrofural
Nitrendipine
Nitrazepam
Nimodipine
Nimesulide
Nilutamide
Nikethamide
Nifuroxazide
Niflumic acid
Nifedipine 2/1
Nicotinic acid
Nicotine suggested
Nicotinamide
Niclosamide 1/1 (polymorphic)
Nicergoline
Nevirapine 1/2
Netilmicin sulphate
Neostigmine methylsulphate
Neostigmine bromide
Neomycin sulphate
Neohesperidin-dihydrochalcone 5/1
Naproxen sodium 1/1
Naproxen sodium 2/1 (polymorphic)
Naproxen sodium 4/1
Naproxen 1.5/1
Naphazoline nitrate
Naphazoline hydrochloride
Nandrolone decanoate
Naltrexone hydrochloride 4/1
Naloxone hydrochloride 2/1
Nalidixic acid
Naftidrofuryl hydrogen oxalate
Nadolol
Nabumetone
N-Acetyltyrosine
N-Acetyltryptophan
Mupirocin calcium 2/1
Mupirocin
Moxonidine
Moxifloxacin hydrochloride 1/1
Moxidectin
Morphine sulphate 5/1
Morphine hydrochloride 3/1
Morantel hydrogen tartrate
Mometasone furoate
Molsidomine
Modafinil
Mitoxantrone hydrochloride
Mitomycin 1.5/1
Misoprostol
Mirtazapine 1/2
Minoxidil
Minocycline hydrochloride 2/1
Midazolam
Miconazole nitrate
Miconazole 1/2
Mianserin hydrochloride
Mexiletine hydrochloride
Metronidazole benzoate 1/1
Metronidazole
Metrifonate
Metoprolol tartrate
Metoprolol succinate
Metolazone
Metoclopramide hydrochloride 1/1
Metoclopramide
Metixene hydrochloride 1/1
Methylrosanilinium chloride
Methylprednisolone hydrogen succinate
Methylprednisolone acetate
Methylprednisolone
Methylphenobarbital
Methylergometrine maleate
Methylene blue 5/1
Methylene blue 3/1
Methylene blue 4/1
Methyldopa 1.5/1
Methylatropine nitrate
Methylatropine bromide
Methyl parahydroxybenzoate
Methyl nicotinate
Methotrexate suggested
Methionine
Methenamine
Methaqualone
Methadone hydrochloride
Metformin hydrochloride
Metamizole sodium
Mestranol
Mesterolone
Mesna 1/1
Mesalazine
Mercaptopurine 1/1
Mepyramine maleate
Meprobamate
Mepivacaine hydrochloride
Menthol
Menadione
Meglumine
Megestrol acetate
Mefloquine hydrochloride suggested
Mefenamic acid
Medroxyprogesterone acetate
Meclozine hydrochloride
Mebendazole
Marbofloxacin
Maprotiline hydrochloride
Mannitol suggested
Mannitol 1/2
Manganese glycerophosphate
Manganese gluconate
Maltitol
Malic acid 1/1
Maleic acid
Malathion
Magnesium stearate 1/1
Magnesium stearate 2/1
Magnesium stearate 3/1
Magnesium pidolate
Magnesium lactate 2/1
Magnesium lactate 6/1
Magnesium glycerophosphate 1/1 (suggested)
Magnesium gluconate
Magnesium citrate 14/1
Magnesium citrate 10/1
Magnesium citrate 2/1
Magnesium aspartate 2/1
Magnesium aspartate 3/1
Magnesium aspartate 1/1
Magnesium aspartate 4/1
Magnesium acetate 4/1
Magnesium acetate 1/1
Lysine hydrochloride 2/1
Lysine acetate
Lynestrenol
Lymecycline
Lovastatin
Lorazepam suggested
Loratadine
Loperamide oxide 2.25/1
Loperamide hydrochloride 4/1
Lomustine
Lobeline hydrochloride
Lithium citrate 1/1
Lithium citrate 4/1
Lithium citrate 5/1
Lisinopril 2/1
Lisinopril 1/1
Liothyronine sodium
Lindane
Lincomycin hydrochloride 1/1
Lidocaine hydrochloride 1/1
Lidocaine
Levothyroxine sodium 1/1 (suggested)
Levothyroxine sodium 5/1
Levonorgestrel
Levomethadone hydrochloride
Levomepromazine maleate
Levomepromazine hydrochloride
Levomenthol
Levodropropizine
Levodopa
Levocarnitine
Levocabastine hydrochloride
Levamisole hydrochloride
Levamisole
Leucine
Letrozole
Leflunomide
Lansoprazole
Lamivudine 1/5
Lamivudine 1/2
Lactulose 3/1
Lactose 1/1
Lactobionic acid
Lactitol 1/1
Lactitol 3/1
Lactitol 2/1
Lactic acid 1/1
Labetalol hydrochloride
Ketotifen hydrogen fumarate
Ketorolac trometamol
Ketoprofen
Ketoconazole
Ketobemidone hydrochloride
Ketamine hydrochloride
Kanamycin monosulphate
Kanamycin acid sulphate
Josamycin propionate
Josamycin
Ivermectin
Itraconazole
Isradipine
Isoxsuprine hydrochloride
Isotretinoin
Isoprenaline sulphate
Isoprenaline hydrochloride
Isoniazid
Isoleucine
Isoconazole nitrate
Isoconazole
Ipratropium bromide
Ioxaglic acid
Iotrolan
Iotalamic acid
Iopanoic acid
Iopamidol 1/1 (suggested)
Iopamidol 5/1 (suggested)
Iohexol
Inositol 2/1
Indometacin
Indinavir sulphate suggested
Indapamide 1/1
Imipramine hydrochloride
Imipenem 1/1
Ifosfamide
Idoxuridine
Ibuprofen
Hyoscyamine sulphate suggested
Hyoscine hydrobromide 3/1
Hyoscine hydrobromide 1/2
Hyoscine hydrobromide 1.5/1
Hyoscine butylbromide
Hyoscine
Hymecromone
Hydroxyzine hydrochloride
Hydroxyethyl salicylate
Hydroxycarbamide
Hydroxocobalamin sulphate
Hydroxocobalamin chloride
Hydroxocobalamin acetate
Hydromorphone hydrochloride
Hydrocortisone hydrogen succinate
Hydrocortisone acetate
Hydrocortisone
Hydrocodone hydrogen tartrate 2.5/1
Hydrochlorothiazide
Hydralazine hydrochloride
Homatropine methylbromide
Homatropine hydrobromide
Histidine hydrochloride 1/1
Histidine hydrochloride 2/1 (DL)
Histidine suggested
Histamine phosphate 1/1
Histamine dihydrochloride
Histamine
Hexylresorcinol
Hexobarbital
Hexetidine
Hexamidine diisetionate
Heptaminol hydrochloride
Haloperidol decanoate
Haloperidol
Halofantrine hydrochloride
Guanethidine monosulphate
Guaifenesin
Guaiacol
Griseofulvin
Granisetron hydrochloride
Gramicidin
Goserelin
Glycine
Glycerol triacetate
Glycerol monostearate
Glycerol monooleate
Glycerol monocaprylocaprate
Glycerol monocaprylate
Glycerol distearate
Glycerol dibehenate
Glutathione
Glutamic acid 1/1
Glucose 1/1
Glipizide
Glimepiride
Gliclazide
Glibenclamide
Gentamicin sulphate
Gemfibrozil
Gemcitabine hydrochloride
Gallamine triethiodide
Galactose
Fusidic acid
Furosemide
Fructose 5/1
Fructose 1/1
Framycetin sulphate
Fosfomycin trometamol
Fosfomycin sodium
Fosfomycin calcium
Foscarnet sodium 6/1
Formoterol fumarate 2/1
Folic acid
Fluvoxamine maleate
Flutrimazole
Fluticasone propionate
Flutamide
Fluspirilene
Flurbiprofen 2/3
Flurazepam monohydrochloride
Fluphenazine enantate
Fluphenazine dihydrochloride
Fluphenazine decanoate
Flupentixol Dihydrochloride
Fluoxetine hydrochloride
Fluorouracil
Fluorodopa
Fluorescein sodium 8/1
Fluorescein sodium 2/1
Fluorescein
Fluocortolone pivalate
Fluocinolone acetonide
Flunixin meglumine
Flunitrazepam
Flunarizine dihydrochloride
Flumetasone pivalate
Flumequine
Flumazenil
Fludrocortisone acetate
Fludarabine phosphate
Flucytosine
Fluconazole 1/1
Flucloxacillin sodium suggested
Flucloxacillin magnesium 8/1
Flubendazole
Flecainide acetate
Flavoxate hydrochloride
Finasteride
Fexofenadine hydrochloride suggested
Ferrous gluconate 2/1
Ferrous fumarate 1/2
Fenticonazole nitrate
Fentanyl citrate
Fentanyl
Fenoterol hydrobromide
Fenofibrate
Fenbufen
Fenbendazole
Felypressin
Felodipine
Felbinac
Febantel
Famotidine
Eugenol
Etoposide 1/1 (polymorphic)
Etomidate
Etofylline
Etofenamate
Etodolac
Etilefrine hydrochloride
Etidronate disodium 1/1
Ethylmorphine hydrochloride
Ethylhexanoic acid
Ethyl parahydroxybenzoate sodium
Ethyl parahydroxybenzoate
Ethyl oleate
Ethosuximide
Ethionamide
Ethinylestradiol
Ethambutol hydrochloride
Ethacrynic acid
Ethacridine lactate
Etamsylate
Estriol
Estradiol valerate
Estradiol benzoate
Estradiol 1/2
Esketamine hydrochloride
Eserine sulphate
Eserine salicylate
Erythromycin stearate
Erythromycin lactobionate 3/1
Erythromycin lactobionate 4/1
Erythromycin lactobionate 5/1
Erythromycin lactobionate 6/1
Erythromycin lactobionate 11/1
Erythromycin ethylsuccinate
Erythromycin estolate suggested
Erythromycin 2/1
Erythromycin 1/1
Erythritol
Ergotamine tartrate 2/1
Ergometrine maleate
Ergocalciferol
Epirubicin hydrochloride
Epinephrine tartrate suggested
Epinephrine 1/2
Ephedrine hydrochloride
Ephedrine 1/2
Enoxolone
Enilconazole
Enalaprilat 2/1
Enalaprilat 3/1
Enalapril maleate
Emetine hydrochloride 7/1
Emetine hydrochloride 5/1
Emedastine difumarate
Edrophonium chloride
Edetic acid
Econazole nitrate
Econazole
Ebastine
Droperidol
Doxylamine hydrogen succinate
Doxycycline hyclate
Doxycycline 1/1
Doxorubicin hydrochloride
Doxepin hydrochloride
Doxazosin mesilate 2/1
Doxapram hydrochloride
Dosulepin hydrochloride
Dorzolamide hydrochloride
Dopexamine dihydrochloride
Dopamine hydrochloride
Domperidone maleate 2.5/1
Domperidone
Dodecyl gallate
Docusate sodium
Dobutamine hydrochloride
DL-Methionine
DL-alpha-Tocopheryl hydrogen succinate
Dithranol
Disulfiram
Disopyramide phosphate
Dirithromycin
Dipyridamole
Diprophylline
Dipotassium clorazepate
Dipivefrin hydrochloride
Diphenoxylate hydrochloride
Diphenhydramine hydrochloride
Diosmin suggested
Dinoprostone
Dinoprost trometamol