Hydrates Database

The hydrates database contains all pharmaceuticals monographed in the European Pharmacopeia (Pharmacopeia Europa 6.2, 2012) and collates information about known hydrates of these drug substances as well as links where relevant experimental data can be found. If there is no hydrate data under a particular entry then it is because we are not aware that it forms a hydrate - please update us if ay are missing. Note that the database includes reported hydrates even where there is no crystallographic data and so it complements other resources such as the Cambridge Structural Database.

Click on the headings to sort the columns as you wish. If you want to search by stoichiometry or by hydrate type please use the search function on the right or our detailed search interface.

Name Stoichiometry Crystal Datasort icon Neutron Data PXRD data IR data Raman data DSC data TGA data Moisture data
Articaine hydrochloride
Ascorbic acid
Ascorbyl palmitate
Astemizole
Atenolol
Atracurium besilate
Atropine
Atropine sulphate
Azelastine hydrochloride possibly
Azithromycin 1/1
Bacampicillin hydrochloride
Bacitracin
Bacitracin zinc
Baclofen 1/1
Bambuterol hydrochloride
Barbital
Beclometasone dipropionate 1/1
Bendroflumethiazide
Benfluorex hydrochloride
Benperidol
Benserazide hydrochloride
Benzalkonium chloride
Benzathine benzylpenicillin 4/1
Benzbromarone
Benzethonium chloride
Benzocaine
Benzoic acid
Benzoyl peroxide
Benzyl benzoate
Benzylpenicillin potassium
Benzylpenicillin procaine
Benzylpenicillin sodium
Betacarotene
Betahistine dihydrochloride
Betahistine mesilate
Betamethasone
Betamethasone acetate
Betamethasone dipropionate
Betamethasone sodium phosphate
Betamethasone valerate
Betaxolol hydrochloride
Bezafibrate
Bifonazole
Biotin
Biperiden hydrochloride
Bisacodyl
Bisoprolol fumarate
Bleomycin sulphate
Bromazepam
Bromhexine hydrochloride
Bromocriptine mesylate
Bromperidol
Bromperidol decanoate
Brompheniramine maleate
Brotizolam
Budesonide
Bufexamac
Buflomedil hydrochloride
Bumetanide
Bupivacaine hydrochloride 1/1 (S)
Spiramycin
Spectinomycin sulphate 4/1
Sotalol hydrochloride
Sorbic acid
Sodium valproate
Sodium salicylate 6/1
Sodium propyl parahydroxybenzoate
Sodium propionate
Sodium phenylbutyrate
Sodium methyl parahydroxybenzoate
Sodium iodohippurate
Sodium hyaluronate
Sodium fusidate
Sodium cyclamate
Sodium caprylate
Sodium calcium edetate 2/1
Sodium benzoate 0.28/1
Sodium aurothiomalate 1/1
Sodium ascorbate
Sodium aminosalicylate 2/1
Sodium alginate
S-lactic acid
Simvastatin
Sertraline hydrochloride 1/1 (suggested)
Sertaconazole nitrate 1/1
Selegiline hydrochloride
Scopolamine butylbromide
Scopolamine suggested
Salmeterol xinafoate
Salicylic acid
Salbutamol sulphate
Salbutamol
Saccharin
Rutoside 3/1
RRR-alpha Tocopheryl hydrogen succinate
RRR-alpha Tocopheryl acetate
RRR-alpha Tocopherol
Roxithromycin
Ropivacaine hydrochloride 1/1
Rocuronium bromide
Ritonavir 3/1
Risperidone
Rilmenidine dihydrogen phosphate
Rifamycin sodium
Rifampicin 2/1
Rifampicin 1/1
Rifabutin
Riboflavin sodium phosphate suggested
Riboflavin
Ribavirin
Resorcinol
Reserpine
Repaglinide
Ranitidine hydrochloride
Ramipril 1/1
Racecadotril
Quinine sulphate 8/1
Quinine hydrochloride 2/1
Quinidine sulphate 3.5/1
Pyrrolidone
Pyrimethamine
Pyridoxine hydrochloride
Pyridostigmine bromide
Pyrazinamide
Pyrantel embonate
Pseudoephedrine hydrochloride
Proxyphylline
Protirelin
Propyphenazone
Propylthiouracil
Propyl parahydroxybenzoate
Propylene glycol monostearate
Propylene glycol monolaurate
Propylene glycol dilaurate
Propylene glycol
Propranolol hydrochloride
Propofol
Propantheline bromide
Propafenone hydrochloride
Propacetamol hydrochloride
Promethazine hydrochloride
Promazine hydrochloride
Proguanil hydrochloride
Progesterone
Prochlorperazine maleate
Procaine hydrochloride
Procaine benzylpenicillin
Procainamide hydrochloride
Probenecid
Primidone
Primaquine diphosphate
Prilocaine hydrochloride
Prilocaine
Prednisone
Prednisolone sodium phosphate
Prednisolone pivalate
Prednisolone acetate
Prednicarbate
Prazosin hydrochloride 2/1
Prazepam
Pravastatin sodium
Potassium sorbate
Potassium hydrogen tartrate
Potassium hydrogen aspartate 1/2
Potassium clavulanate
Potassium citrate 2/1
Potassium acetate 1/2
Potassium acetate 1.5/1
Potassium acetate 3/1
Potassium acetate 2/1
Potassium acetate 1/1
Polymyxin B sulphate
Pivmecillinam hydrochloride
Pivampicillin
Piretanide
Pirenzepine dihydrochloride 1/1
Piperazine citrate
Piperazine adipate
Piperacillin sodium 1/1
Piperacillin sodium 2.5/1
Pindolol
Pimozide
Pimobendan 1/1
Pilocarpine nitrate
Pilocarpine hydrochloride
Phytosterol
Phytomenadione
Physostigmine sulphate
Physostigmine salicylate
Phthalylsulfathiazole
Pholcodine
Phenytoin sodium 8/1
Phenytoin sodium 4/1
Phenytoin sodium 1/1 (polymorphic)
Phenytoin
Phenylpropanolamine hydrochloride
Phenylmercuric nitrate
Phenylmercuric borate
Phenylmercuric acetate
Phenylephrine hydrochloride
Phenylephrine
Phenylbutazone 1/1
Phenylalanine 1/1
Phentolamine mesilate
Phenoxymethylpenicillin potassium
Phenoxymethylpenicillin
Phenoxyethanol
Phenolsulfonphthalein
Phenolphthalein
Phenobarbital sodium
Phenobarbital 1/2
Pheniramine maleate
Phenazone
Pethidine hydrochloride
Perphenazine
Perindopril tert-butylamine
Pergolide mesilate
Pentoxyverine hydrogen citrate
Pentoxifylline
Pentobarbital sodium
Pentobarbital
Buprenorphine
Bupreorphine hydrochloride
Buserelin
Buspirone hydrochloride
Busulfan
Butylhydroxyanisole
Butylhydroxytoluene
Butyl parahydroxybenzoate
Cabergoline
Calcifediol
Calcitriol
Calcium dobesilate 1/1
Calcium folinate
Calcium glucoheptonate 3.5/1
Calcium gluconate
Calcium glycerophosphate 1/1
Calcium glycerophosphate 2/1
Calcium lactate 1/1
Calcium lactate 3/1
Calcium lactate 5/1
Calcium levofolinate 5/1
Calcium levulinate 2/1
Calcium pantothenate 1/1
Calcium pantothenate 3/4
Calcium stearate 3/4
Camphor (D)
Camphor racemic
Caprylic acid
Captopril
Carbachol
Carbasalate calcium
Carbidopa
Carbimazole
Carbocisteine
Carboplatin
Carboprost trometamol
Carisoprodol
Carmustine
Carteolol hydrochloride
Carvedilol
Cefaclor 1/1
Cefalexin 1/1
Cefalexin 1/2
Cefalotin sodium
Cefamandole nafate 2.5/1
Cefapirin sodium
Cefatrizine propylene glycol
Cefazolin sodium 1.5/1
Cefazolin sodium 1/1
Cefepime dihydrochloride 1/1
Cefepime dihydrochloride 2/1
Cefixime 3/1
Cefoperazone sodium
Cefotaxime sodium
Cefoxitin sodium
Cefradine
Ceftazidime 5/1
Ceftazidime 1.5/1
Ceftriaxone sodium 3.5/1
Cefuroxime axetil
Cefuroxime sodium
Celiprolol hydrochloride 1/1
Cetirizine dihydrochloride
Chenodeoxycholic acid
Chloral hydrate
Chlorambucil
Chloramphenicol
Chloramphenicol palmitate
Chloramphenicol sodium succinate
Chlorcyclizine hydrochloride
Chlordiazepoxide
Chlordiazepoxide hydrochloride
Chlorhexidine diacetate
Chlorhexidine dihydrochloride
Chlorocresol
Chlorothiazide
Chlorphenamine maleate
Chlorpropamide
Chlorprothixene hydrochloride
Chlortalidone
Chlortetracycline hydrochloride
Cholecalciferol
Ciclopirox
Ciclopirox olamine
Ciclosporin
Cilastatin sodium
Cilazapril
Cimetidine 1/1 (polymorphic)
Cinchocaine hydrochloride
Cineole
Cinnarizine
Ciprofibrate
Ciprofloxacin suggested
Ciprofloxacin hydrochloride 1/1
Cisapride 1/1
Cisapride tartrate
Cisplatin
Cladribine
Clebopride malate
Clemastine fumarate
Clenbuterol hydrochloride
Clindamycin phosphate
Clioquinol
Clobazam
Clobetasol propionate
Clobetasone butyrate
Clodronate disodium 4/1
Clofazimine
Clofibrate
Clomifene citrate
Clomipramine hydrochloride
Clonazepam
Clonidine hydrochloride
Clopamide
Closantel sodium 2/1
Clotrimazole
Cloxacillin sodium 1/1
Clozapine
Cocaine hydrochloride
Codeine
Codeine hydrochloride 2/1
Codeine phosphate 1/2
Codeine phosphate 1/1
Codeine phosphate 1.5/1
Colistin sulphate
Cresol
Crotamiton
Cyclizine hydrochloride
Cyclopentolate hydrochloride
Cyproterone acetate
Cysteine hydrochloride 1/1 (DL)
Cystine
Cytarabine
Dacarbazine
Daunorubicin hydrochloride
D-Camphor
Decyl oleate
Deferoxamine mesilate
Dembrexine hydrochloride 1/1
Demeclocycline hydrochloride
Deptropine citrate
Dequalinium chloride
Desflurane
Desipramine hydrochloride
Deslanoside
Desmopressin
Desogestrel
Desoxycortone acetate
Detomidine hydrochloride 1/1
Dexamethasone
Dexamethasone acetate 1.5/1
Dexamethasone isonicotinate
Dexamethasone sodium phosphate
Dexpanthenol
Dextromethorphan hydrobromide 1/1
Dextromoramide tartrate
Dextropropoxyphene hydrochloride
Diazepam
Diazoxide
Dibrompropamidine diisetionate
Dibutyl phthalate
Diclazuril
Diclofenac potassium 2/1
Dicloxacillin sodium 1/1
Dicycloverine hydrochloride
Dienestrol
Diethylcarbamazine citrate
Diethyl phthalate
Diethylstilbestrol
Digitoxin
Digoxin 1/4
Digoxin 1/2
Dihydrocodeine hydrogen tartrate
Dihydroergocristine mesylate suggested
Dihydroergotamine mesylate suggested
Dihydroergotamine tartrate
Dihydrostreptomycin sulphate
Dihydrotachysterol
Diltiazem hydrochloride
Dimenhydrinate 1/2
Dimenhydrinate 2/1
Dimercaprol
Dimetindene maleate
Dinoprostone
Dinoprost trometamol
Diosmin suggested
Diphenhydramine hydrochloride
Diphenoxylate hydrochloride
Dipivefrin hydrochloride
Dipotassium clorazepate
Diprophylline
Dipyridamole
Dirithromycin
Disopyramide phosphate
Disulfiram
Dithranol
DL-Methionine
DL-alpha-Tocopheryl hydrogen succinate
Dobutamine hydrochloride
Docusate sodium
Dodecyl gallate
Domperidone
Dopamine hydrochloride
Dopexamine dihydrochloride
Dorzolamide hydrochloride
Dosulepin hydrochloride
Doxapram hydrochloride
Doxepin hydrochloride
Doxorubicin hydrochloride
Doxycycline hyclate
Doxycycline 1/1
Doxylamine hydrogen succinate
Droperidol
Ebastine
Econazole
Econazole nitrate
Edetic acid
Edrophonium chloride
Emedastine difumarate
Emetine hydrochloride 7/1
Emetine hydrochloride 5/1
Enalaprilat 2/1
Enalapril maleate
Enilconazole
Enoxolone
Ephedrine hydrochloride
Epinephrine 1/2
Epinephrine tartrate suggested
Epirubicin hydrochloride
Ergocalciferol
Ergometrine maleate
Ergotamine tartrate 2/1
Erythritol
Erythromycin 1/1
Erythromycin estolate suggested
Erythromycin ethylsuccinate
Erythromycin lactobionate 3/1
Erythromycin lactobionate 4/1
Erythromycin lactobionate 5/1
Erythromycin lactobionate 6/1
Erythromycin lactobionate 11/1
Erythromycin stearate
Eserine salicylate
Eserine sulphate
Esketamine hydrochloride
Estradiol benzoate
Estradiol valerate
Estriol
Ethacrynic acid
Etamsylate
Ethambutol hydrochloride
Ethinylestradiol
Ethionamide
Ethosuximide
Ethylhexanoic acid
Ethylmorphine hydrochloride
Ethyl oleate
Ethyl parahydroxybenzoate
Ethyl parahydroxybenzoate sodium
Etilefrine hydrochloride
Etodolac
Etofenamate
Etofylline
Etomidate
Eugenol
Famotidine
Febantel
Felbinac
Felodipine
Felypressin
Fenbendazole
Fenbufen
Fenofibrate
Fenoterol hydrobromide
Fentanyl
Fentanyl citrate
Fenticonazole nitrate
Ferrous fumarate 1/2
Ferrous gluconate 2/1
Fexofenadine hydrochloride suggested
Finasteride
Flavoxate hydrochloride
Flecainide acetate
Flubendazole
Flucloxacillin magnesium 8/1
Flucloxacillin sodium suggested
Flucytosine
Fludarabine phosphate
Fludrocortisone acetate
Flumazenil
Flumequine
Flumetasone pivalate
Flunarizine dihydrochloride
Flunitrazepam
Flunixin meglumine
Fluocinolone acetonide
Fluocortolone pivalate
Fluorescein
Fluorescein sodium 2/1
Fluorodopa
Fluorouracil
Fluoxetine hydrochloride
Flupentixol Dihydrochloride
Fluphenazine decanoate
Fluphenazine dihydrochloride
Fluphenazine enantate
Flurazepam monohydrochloride
Fluspirilene
Flutamide
Fluticasone propionate
Zuclopenthixol decanoate 2/1
Flutrimazole
Fluvoxamine maleate
Folic acid
Foscarnet sodium 6/1
Fosfomycin calcium
Fosfomycin sodium
Fosfomycin trometamol
Framycetin sulphate
Fructose 5/1
Fructose 1/1
Furosemide
Fusidic acid
Galactose
Gallamine triethiodide
Gemcitabine hydrochloride
Gemfibrozil
Gentamicin sulphate
Glibenclamide
Gliclazide
Glimepiride
Glipizide
Glutathione
Glycerol dibehenate
Glycerol distearate
Glycerol monocaprylate
Glycerol monocaprylocaprate
Glycerol monooleate
Glycerol monostearate
Glycerol triacetate
Glycine
Goserelin
Gramicidin
Granisetron hydrochloride
Griseofulvin
Guaiacol
Guaifenesin
Guanethidine monosulphate
Halofantrine hydrochloride
Haloperidol
Haloperidol decanoate
Heptaminol hydrochloride
Hexamidine diisetionate
Hexetidine
Hexobarbital
Hexylresorcinol
Histamine
Histamine dihydrochloride
Histidine suggested
Homatropine hydrobromide
Homatropine methylbromide
Hydralazine hydrochloride
Hydrochlorothiazide
Hydrocodone hydrogen tartrate 2.5/1
Hydrocortisone
Hydrocortisone acetate
Hydrocortisone hydrogen succinate
Hydromorphone hydrochloride
Hydroxocobalamin acetate
Hydroxocobalamin chloride
Hydroxocobalamin sulphate
Hydroxycarbamide
Hydroxyethyl salicylate
Hydroxyzine hydrochloride
Hymecromone
Hyoscine
Hyoscine butylbromide
Hyoscine hydrobromide 3/1
Hyoscyamine sulphate suggested
Ibuprofen
Idoxuridine
Ifosfamide
Imipramine hydrochloride
Indapamide 1/1
Indinavir sulphate suggested
Indometacin
Iohexol
Iopamidol 1/1 (suggested)
Iopamidol 5/1 (suggested)
Iopanoic acid
Iotalamic acid
Iotrolan
Ioxaglic acid
Ipratropium bromide
Isoconazole
Isoconazole nitrate
Isoleucine
Isoniazid
Isoprenaline hydrochloride
Isoprenaline sulphate
Isotretinoin
Isoxsuprine hydrochloride
Isradipine
Itraconazole
Ivermectin
Josamycin
Josamycin propionate
Kanamycin acid sulphate
Kanamycin monosulphate
Ketamine hydrochloride
Ketobemidone hydrochloride
Ketoconazole
Ketoprofen
Ketorolac trometamol
Ketotifen hydrogen fumarate
Labetalol hydrochloride
Lactic acid 1/1
Lactobionic acid
Lansoprazole
Leflunomide
Letrozole
Leucine
Levamisole
Levamisole hydrochloride
Levocabastine hydrochloride
Levocarnitine
Levodopa
Levodropropizine
Levomenthol
Levomepromazine hydrochloride
Levomepromazine maleate
Levomethadone hydrochloride
Levonorgestrel
Levothyroxine sodium 1/1 (suggested)
Lidocaine
Lindane
Liothyronine sodium
Lisinopril 2/1
Lisinopril 1/1
Lobeline hydrochloride
Lomustine
Loratadine
Lorazepam suggested
Lovastatin
Lymecycline
Lynestrenol
Lysine acetate
Magnesium aspartate 2/1
Magnesium citrate 14/1
Magnesium citrate 2/1
Magnesium gluconate
Magnesium glycerophosphate 1/1 (suggested)
Magnesium lactate 2/1
Magnesium lactate 6/1
Magnesium pidolate
Magnesium stearate 1/1
Magnesium stearate 2/1
Magnesium stearate 3/1
Malathion
Maleic acid
Maltitol
Manganese gluconate
Manganese glycerophosphate
Mannitol suggested
Mannitol 1/2
Maprotiline hydrochloride
Marbofloxacin
Mebendazole
Meclozine hydrochloride
Medroxyprogesterone acetate
Mefenamic acid
Mefloquine hydrochloride suggested
Megestrol acetate
Meglumine
Menadione
Menthol
Mepivacaine hydrochloride
Meprobamate
Mepyramine maleate
Mesalazine
Mesterolone
Mestranol
Metamizole sodium
Metformin hydrochloride
Methadone hydrochloride
Methaqualone
Methenamine
Methionine
Methotrexate suggested
Methylatropine bromide
Methylatropine nitrate
Methylene blue 3/1
Methylene blue 4/1
Methylergometrine maleate
Methyl nicotinate
Methyl parahydroxybenzoate
Methylphenobarbital
Methylprednisolone
Methylprednisolone acetate
Methylprednisolone hydrogen succinate
Methylrosanilinium chloride
Metoclopramide
Metolazone
Metoprolol succinate
Metoprolol tartrate
Metrifonate
Metronidazole
Mexiletine hydrochloride
Mianserin hydrochloride
Miconazole nitrate
Midazolam
Minocycline hydrochloride 2/1
Minoxidil
Misoprostol
Mitoxantrone hydrochloride
Modafinil
Molsidomine
Mometasone furoate
Morantel hydrogen tartrate
Moxidectin
Moxonidine
Mupirocin
Mupirocin calcium 2/1
Nabumetone
N-Acetyltryptophan
N-Acetyltyrosine
Nadolol
Naftidrofuryl hydrogen oxalate
Nalidixic acid
Nandrolone decanoate
Naphazoline hydrochloride
Naphazoline nitrate
Naproxen 1.5/1
Naproxen sodium 2/1 (polymorphic)
Naproxen sodium 4/1
Neomycin sulphate
Neostigmine bromide
Neostigmine methylsulphate
Netilmicin sulphate
Nicergoline
Nicotinamide
Nicotine suggested
Nicotinic acid
Nifedipine 2/1
Niflumic acid
Nifuroxazide
Nikethamide
Nilutamide
Nimesulide
Nimodipine
Nitrazepam
Nitrendipine
Nitrofural
Nizatidine
Nomegestrol acetate
Noradrenaline hydrochloride suggested
Noradrenaline tartrate suggested
Norepinephrine hydrochloride suggested
Norepinephrine tartrate suggested
Norethisterone
Norethisterone acetate
Norfloxacin 2.5/1
Norfloxacin 3/1
Norfloxacin 5/1
Norgestimate
Norgestrel
Nortriptyline hydrochloride
Noscapine
Noscapine hydrochloride suggested
Nystatin
Ofloxacin
Oleic acid
Olsalazine sodium
Omeprazole
Omeprazole sodium 1/1
Orciprenaline sulphate
Orphenadrine citrate
Orphenadrine hydrochloride
Ouabain 2/1
Ouabain 3/1
Ouabain 4/1
Ouabain 8/1
Ouabain 9/1
Ouabain 10/1
Oxacillin sodium 1/1
Oxaliplatin
Oxazepam
Oxeladin hydrogen citrate
Oxfendazole
Oxitropium bromide
Oxolinic acid
Oxprenolol hydrochloride
Oxybuprocaine hydrochloride
Oxybutynin hydrochloride
Oxycodone hydrochloride suggested
Oxytocin
Paclitaxel 2/1
Palmitic acid
Pamidronate disodium 4/1
Pamidronate disodium 3/1
Pancuronium bromide
Pantoprazole sodium 1.5/1
Pantoprazole sodium 1/1
Pantoprazole sodium 0.5/1
Pantoprazole sodium 2/1
Papaverine hydrochloride
Penbutolol sulphate
Penicillamine
Pentazocine suggested
Arginine aspartate
Antazoline hydrochloride
Ampicillin sodium
Amoxicillin sodium
Amobarbital sodium
Amobarbital
Amlodipine besilate 1/1
Amitriptyline hydrochloride
Amisulpride
Amiodarone hydrochloride
Aminoglutethimide
Aminocaproic acid
4-Aminobenzoic acid
Amiloride hydrochloride 2/1 (polymorphic)
Amikacin sulphate
Amikacin
Amidotrizoic acid 2/1
Amfetamine sulphate
Ambroxol hydrochloride
Amantadine hydrochloride
Alverine citrate
Altizide
Alprostadil
Alprenolol hydrochloride
alphacyclodextrin 11/1
all-rac-alpha Tocopherol acetate
all-rac-alpha Tocopherol
Allopurinol
Allantoin
Alginic acid
Alfuzosin hydrochloride 2/1
Alfadex
Alfacalcidol
Alcuronium chloride
Albendazole
Alanine
Adrenaline tartrate
Adrenaline
Adipic acid
Adenosine
Adenine
Acitretin
Acetyltyrosine
Acetyltryptophan
Acetylsalicylic acid
beta-Acetyldigoxin
Acetylcysteine
Acetylcholine chloride
Acetazolamide
Acesulfame potassium
Aceclofenac