Hydrates Database

The hydrates database contains all pharmaceuticals monographed in the European Pharmacopeia (Pharmacopeia Europa 6.2, 2012) and collates information about known hydrates of these drug substances as well as links where relevant experimental data can be found. If there is no hydrate data under a particular entry then it is because we are not aware that it forms a hydrate - please update us if ay are missing. Note that the database includes reported hydrates even where there is no crystallographic data and so it complements other resources such as the Cambridge Structural Database.

Click on the headings to sort the columns as you wish. If you want to search by stoichiometry or by hydrate type please use the search function on the right or our detailed search interface.

Namesort icon Stoichiometry Crystal Data Neutron Data PXRD data IR data Raman data DSC data TGA data Moisture data
4-Aminobenzoic acid
Acamprosate calcium
Acarbose
Acebutolol hydrochloride
Aceclofenac
acemetacin 1/1
Acesulfame potassium
Acetazolamide
Acetylcholine chloride
Acetylcysteine
Acetylsalicylic acid
Acetyltryptophan
Acetyltyrosine
Aciclovir 3/2
Aciclovir 2/1
Acitretin
Adenine
Adenosine
Adipic acid
Adrenaline
Adrenaline tartrate
Alanine
Albendazole
Alcuronium chloride
Alfacalcidol
Alfadex
Alfentanil hydrochloride 1/1
Alfuzosin hydrochloride 2/1
Alginic acid
all-rac-alpha Tocopherol
all-rac-alpha Tocopherol acetate
Allantoin
Allopurinol
alphacyclodextrin 6/1 (polymorphic)
alphacyclodextrin 7.5/1
alphacyclodextrin 3/1
alphacyclodextrin 11/1
Alprazolam 2/1
Alprenolol hydrochloride
Alprostadil
Altizide
Alverine citrate
Amantadine hydrochloride
Ambroxol hydrochloride
Amfetamine sulphate
Amidotrizoic acid 2/1
Amikacin
Amikacin sulphate
Amiloride hydrochloride 2/1 (polymorphic)
Aminocaproic acid
Aminoglutethimide
Amiodarone hydrochloride
Amisulpride
Amitriptyline hydrochloride
Amlodipine besilate 2/1
Amlodipine besilate 1/1
Amobarbital
Amobarbital sodium
Amoxicillin 3/1
Amoxicillin sodium
Amphotericin B
Ampicillin 3/1
Ampicillin sodium
Antazoline hydrochloride
Apomorphine hydrochloride 1/1
Arginine 2/1(DL)
Arginine 1/1 (DL)
Arginine 2/1 (L)
Arginine aspartate
Arginine hydrochloride 1/1 (L)
Articaine hydrochloride
Ascorbic acid
Ascorbyl palmitate
Asparagine 1/1
Aspartame 0.5/1
Aspartame 0.67/1
Aspartame 5/3
Aspartic acid 1/1
Astemizole
Atenolol
Atracurium besilate
Atropine
Atropine sulphate
Azathioprine 2/1
Azelastine hydrochloride possibly
Azithromycin 1/1
Azithromycin 2/1
Bacampicillin hydrochloride
Bacitracin
Bacitracin zinc
Baclofen 1/1
Bambuterol hydrochloride
Barbital
Beclometasone dipropionate 1/1
Bendroflumethiazide
Benfluorex hydrochloride
Benperidol
Benserazide hydrochloride
Benzalkonium chloride
Benzathine benzylpenicillin 4/1
Benzbromarone
Benzethonium chloride
Benzocaine
Benzoic acid
Benzoyl peroxide
Benzyl benzoate
Benzylpenicillin potassium
Benzylpenicillin procaine
Benzylpenicillin sodium
beta-Acetyldigoxin
Betacarotene
Betacyclodextrin 12/1
Betacyclodextrin 11/1
Betacyclodextrin 9/1
Betacyclodextrin 1/1
Betahistine dihydrochloride
Betahistine mesilate
Betamethasone
Betamethasone acetate
Betamethasone dipropionate
Betamethasone sodium phosphate
Betamethasone valerate
Betaxolol hydrochloride
Bezafibrate
Bifonazole
Biotin
Biperiden hydrochloride
Bisacodyl
Bisoprolol fumarate
Bleomycin sulphate
Bromazepam
Bromhexine hydrochloride
Bromocriptine mesylate
Bromperidol
Bromperidol decanoate
Brompheniramine maleate
Brotizolam
Budesonide
Bufexamac
Buflomedil hydrochloride
Bumetanide
Bupivacaine hydrochloride 1/1 (DS)
Bupivacaine hydrochloride 1/1 (S)
Buprenorphine
Bupreorphine hydrochloride
Buserelin
Buspirone hydrochloride
Busulfan
Butyl parahydroxybenzoate
Butylhydroxyanisole
Butylhydroxytoluene
Cabergoline
Caffeine 0.8/1
Calcifediol
Calcipotriol 1/1
Calcitriol
Calcium acetate 1/1
Calcium ascorbate 2/1
Calcium dobesilate 1/1
Calcium folinate
Calcium glucoheptonate 3.5/1
Calcium gluconate
Calcium glycerophosphate 1/1
Calcium glycerophosphate 2/1
Calcium lactate 1/1
Calcium lactate 3/1
Calcium lactate 5/1
Calcium levofolinate 5/1
Calcium levulinate 2/1
Calcium pantothenate 1/1
Calcium pantothenate 3/4
Calcium stearate 3/4
Camphor (D)
Camphor racemic
Caprylic acid
Captopril
Carbachol
Carbamazepine 2/1
Carbasalate calcium
Carbidopa
Carbimazole
Carbocisteine
Carboplatin
Carboprost trometamol
Carisoprodol
Carmustine
Carteolol hydrochloride
Carvedilol
Cefaclor 2/1
Cefaclor 1/1
Cefadroxil 1/1
Cefalexin 1/1
Cefalexin 1/2
Cefalotin sodium
Cefamandole nafate 2.5/1
Cefapirin sodium
Cefatrizine propylene glycol
Cefazolin sodium 5/1
Cefazolin sodium 1.5/1
Cefazolin sodium 1/1
Cefepime dihydrochloride 1/1
Cefepime dihydrochloride 2/1
Cefixime 3/1
Cefoperazone sodium
Cefotaxime sodium
Cefoxitin sodium
Cefradine
Ceftazidime 5/1
Ceftazidime 1.5/1
Ceftriaxone sodium 3.5/1
Cefuroxime axetil
Cefuroxime sodium
Celiprolol hydrochloride 1/1
Cetirizine dihydrochloride
Chenodeoxycholic acid
Chloral hydrate
Chlorambucil
Chloramphenicol
Chloramphenicol palmitate
Chloramphenicol sodium succinate
Chlorcyclizine hydrochloride
Chlordiazepoxide
Chlordiazepoxide hydrochloride
Chlorhexidine diacetate
Chlorhexidine dihydrochloride
Chlorobutanol 1/2
Chlorocresol
Chloroquine phosphate 1/1
Chlorothiazide
Chlorphenamine maleate
Chlorpromazine hydrochloride 1/2
Chlorpropamide
Chlorprothixene hydrochloride
Chlortalidone
Chlortetracycline hydrochloride
Cholecalciferol
Cholesterol 1/1
Ciclopirox
Ciclopirox olamine
Ciclosporin
Cilastatin sodium
Cilazapril
Cimetidine 1/1 (polymorphic)
Cimetidine hydrochloride 1/1
Cinchocaine hydrochloride
Cineole
Cinnarizine
Ciprofibrate
Ciprofloxacin 3.7/1
Ciprofloxacin 14.5/3
Ciprofloxacin suggested
Ciprofloxacin hydrochloride 1/1
Ciprofloxacin hydrochloride 1.34/1
Cisapride 1/1
Cisapride tartrate
Cisplatin
Citric acid 1/1
Cladribine
Clarithromycin 1/1
Clebopride malate
Clemastine fumarate
Clenbuterol hydrochloride
Clindamycin hydrochloride 1/1
Clindamycin phosphate
Clioquinol
Clobazam
Clobetasol propionate
Clobetasone butyrate
Clodronate disodium 4/1
Clofazimine
Clofibrate
Clomifene citrate
Clomipramine hydrochloride
Clonazepam
Clonidine hydrochloride
Clopamide
Closantel sodium 2/1
Clotrimazole
Cloxacillin sodium 1/1
Clozapine
Cocaine hydrochloride
Codeine
Codeine hydrochloride 2/1
Codeine phosphate 1/2
Codeine phosphate 1/1
Codeine phosphate 1.5/1
Colchicine 1/1
Colchicine 2/1
Colistin sulphate
Cortisone acetate 2/1
Cortisone acetate 1/1
Cresol
Crotamiton
Cyclizine hydrochloride
Cyclopentolate hydrochloride
Cyclophosphamide 1/1
Cyproheptadine hydrochloride 1.5/1
Cyproterone acetate
Cysteine hydrochloride 1/1 (DL)
Cysteine hydrochloride 1/1 (L)
Cystine
Cytarabine
D-Camphor
Dacarbazine
Dapsone 1/3
Daunorubicin hydrochloride
Decyl oleate
Deferoxamine mesilate
Dembrexine hydrochloride 1/1
Demeclocycline hydrochloride
Deptropine citrate
Dequalinium chloride
Desflurane
Desipramine hydrochloride
Deslanoside
Desmopressin
Desogestrel
Desoxycortone acetate
Detomidine hydrochloride 1/1
Dexamethasone
Dexamethasone acetate 1.5/1
Dexamethasone acetate 1/1
Dexamethasone isonicotinate
Dexamethasone sodium phosphate
Dexpanthenol
Dextrin 3/1
Dextromethorphan hydrobromide 1/1
Dextromoramide tartrate
Dextropropoxyphene hydrochloride
Diazepam
Diazoxide
Dibrompropamidine diisetionate
Dibutyl phthalate
Diclazuril
Diclofenac potassium 2/1
Diclofenac potassium 4/1
Diclofenac sodium 4/1 (polymorphic)
Dicloxacillin sodium 1/1
Dicycloverine hydrochloride
Didanosine 0.125/1
Dienestrol
Diethyl phthalate
Diethylcarbamazine citrate
Diethylstilbestrol
Diflunisal 1/1
Digitoxin
Digoxin 1/4
Digoxin 1/2
Dihydralazine sulphate 2.64/1
Dihydrocodeine hydrogen tartrate
Dihydroergocristine mesylate suggested
Dihydroergotamine mesylate suggested
Dihydroergotamine tartrate
Dihydrostreptomycin sulphate
Dihydrotachysterol
Diltiazem hydrochloride
Dimenhydrinate 1/2
Dimenhydrinate 2/1
Dimercaprol
Dimetindene maleate
Dinoprost trometamol
Dinoprostone
Diosmin suggested
Diphenhydramine hydrochloride
Diphenoxylate hydrochloride
Dipivefrin hydrochloride
Dipotassium clorazepate
Diprophylline
Dipyridamole
Dirithromycin
Disopyramide phosphate
Disulfiram
Dithranol
DL-alpha-Tocopheryl hydrogen succinate
DL-Methionine
Dobutamine hydrochloride
Docusate sodium
Dodecyl gallate
Domperidone
Domperidone maleate 2.5/1
Dopamine hydrochloride
Dopexamine dihydrochloride
Dorzolamide hydrochloride
Dosulepin hydrochloride
Doxapram hydrochloride
Doxazosin mesilate 2/1
Doxepin hydrochloride
Doxorubicin hydrochloride
Doxycycline 1/1
Doxycycline hyclate
Doxylamine hydrogen succinate
Droperidol
Ebastine
Econazole
Econazole nitrate
Edetic acid
Edrophonium chloride
Emedastine difumarate
Emetine hydrochloride 7/1
Emetine hydrochloride 5/1
Enalapril maleate
Enalaprilat 2/1
Enalaprilat 3/1
Enilconazole
Enoxolone
Ephedrine 1/2
Ephedrine hydrochloride
Epinephrine 1/2
Epinephrine tartrate suggested
Epirubicin hydrochloride
Ergocalciferol
Ergometrine maleate
Ergotamine tartrate 2/1
Erythritol
Erythromycin 2/1
Erythromycin 1/1
Erythromycin estolate suggested
Erythromycin ethylsuccinate
Erythromycin lactobionate 3/1
Erythromycin lactobionate 4/1
Erythromycin lactobionate 5/1
Erythromycin lactobionate 6/1
Erythromycin lactobionate 11/1
Erythromycin stearate
Eserine salicylate
Eserine sulphate
Esketamine hydrochloride
Estradiol 1/2
Estradiol benzoate
Estradiol valerate
Estriol
Etamsylate
Ethacridine lactate
Ethacrynic acid
Ethambutol hydrochloride
Ethinylestradiol
Ethionamide
Ethosuximide
Ethyl oleate
Ethyl parahydroxybenzoate
Ethyl parahydroxybenzoate sodium
Ethylhexanoic acid
Ethylmorphine hydrochloride
Etidronate disodium 1/1
Etilefrine hydrochloride
Etodolac
Etofenamate
Etofylline
Etomidate
Etoposide 1/1 (polymorphic)
Eugenol
Famotidine
Febantel
Felbinac
Felodipine
Felypressin
Fenbendazole
Fenbufen
Fenofibrate
Fenoterol hydrobromide
Fentanyl
Fentanyl citrate
Fenticonazole nitrate
Ferrous fumarate 1/2
Ferrous gluconate 2/1
Fexofenadine hydrochloride suggested
Finasteride
Flavoxate hydrochloride
Flecainide acetate
Flubendazole
Flucloxacillin magnesium 8/1
Flucloxacillin sodium suggested
Fluconazole 1/1
Flucytosine
Fludarabine phosphate
Fludrocortisone acetate
Flumazenil
Flumequine
Flumetasone pivalate
Flunarizine dihydrochloride
Flunitrazepam
Flunixin meglumine
Fluocinolone acetonide
Fluocortolone pivalate
Fluorescein
Fluorescein sodium 8/1
Fluorescein sodium 2/1
Fluorodopa
Fluorouracil
Fluoxetine hydrochloride
Flupentixol Dihydrochloride
Fluphenazine decanoate
Fluphenazine dihydrochloride
Fluphenazine enantate
Flurazepam monohydrochloride
Flurbiprofen 2/3
Fluspirilene
Flutamide
Fluticasone propionate
Flutrimazole
Fluvoxamine maleate
Folic acid
Formoterol fumarate 2/1
Foscarnet sodium 6/1
Fosfomycin calcium
Fosfomycin sodium
Fosfomycin trometamol
Framycetin sulphate
Fructose 5/1
Fructose 1/1
Furosemide
Fusidic acid
Galactose
Gallamine triethiodide
Gemcitabine hydrochloride
Gemfibrozil
Gentamicin sulphate
Glibenclamide
Gliclazide
Glimepiride
Glipizide
Glucose 1/1
Glutamic acid 1/1
Glutathione
Glycerol dibehenate
Glycerol distearate
Glycerol monocaprylate
Glycerol monocaprylocaprate
Glycerol monooleate
Glycerol monostearate
Glycerol triacetate
Glycine
Goserelin
Gramicidin
Granisetron hydrochloride
Griseofulvin
Guaiacol
Guaifenesin
Guanethidine monosulphate
Halofantrine hydrochloride
Haloperidol
Haloperidol decanoate
Heptaminol hydrochloride
Hexamidine diisetionate
Hexetidine
Hexobarbital
Hexylresorcinol
Histamine
Histamine dihydrochloride
Histamine phosphate 1/1
Histidine suggested
Histidine hydrochloride 1/1
Histidine hydrochloride 2/1 (DL)
Homatropine hydrobromide
Homatropine methylbromide
Hydralazine hydrochloride
Hydrochlorothiazide
Hydrocodone hydrogen tartrate 2.5/1
Hydrocortisone
Hydrocortisone acetate
Hydrocortisone hydrogen succinate
Hydromorphone hydrochloride
Hydroxocobalamin acetate
Hydroxocobalamin chloride
Hydroxocobalamin sulphate
Hydroxycarbamide
Hydroxyethyl salicylate
Hydroxyzine hydrochloride
Hymecromone
Hyoscine
Hyoscine butylbromide
Hyoscine hydrobromide 3/1
Hyoscine hydrobromide 1/2
Hyoscine hydrobromide 1.5/1
Hyoscyamine sulphate suggested
Ibuprofen
Idoxuridine
Ifosfamide
Imipenem 1/1
Imipramine hydrochloride
Indapamide 1/1
Indinavir sulphate suggested
Indometacin
Inositol 2/1
Iohexol
Iopamidol 1/1 (suggested)
Iopamidol 5/1 (suggested)
Iopanoic acid
Iotalamic acid
Iotrolan
Ioxaglic acid
Ipratropium bromide
Isoconazole
Isoconazole nitrate
Isoleucine
Isoniazid
Isoprenaline hydrochloride
Isoprenaline sulphate
Isotretinoin
Isoxsuprine hydrochloride
Isradipine
Itraconazole
Ivermectin
Josamycin
Josamycin propionate
Kanamycin acid sulphate
Kanamycin monosulphate
Ketamine hydrochloride
Ketobemidone hydrochloride
Ketoconazole
Ketoprofen
Ketorolac trometamol
Ketotifen hydrogen fumarate
Labetalol hydrochloride
Lactic acid 1/1
Lactitol 1/1
Lactitol 3/1
Lactitol 2/1
Lactobionic acid
Lactose 1/1
Lactulose 3/1
Lamivudine 1/5
Lamivudine 1/2
Lansoprazole
Leflunomide
Letrozole
Leucine
Levamisole
Levamisole hydrochloride
Levocabastine hydrochloride
Levocarnitine
Levodopa
Levodropropizine
Levomenthol
Levomepromazine hydrochloride
Levomepromazine maleate
Levomethadone hydrochloride
Levonorgestrel
Levothyroxine sodium 1/1 (suggested)
Levothyroxine sodium 5/1
Lidocaine
Lidocaine hydrochloride 1/1
Lincomycin hydrochloride 1/1
Lindane
Liothyronine sodium
Lisinopril 2/1
Lisinopril 1/1
Lithium citrate 1/1
Lithium citrate 4/1
Lithium citrate 5/1
Lobeline hydrochloride
Lomustine
Loperamide hydrochloride 4/1
Loperamide oxide 2.25/1
Loratadine
Lorazepam suggested
Lovastatin
Lymecycline
Lynestrenol
Lysine acetate
Lysine hydrochloride 2/1
Magnesium acetate 4/1
Magnesium acetate 1/1
Magnesium aspartate 2/1
Magnesium aspartate 3/1
Magnesium aspartate 1/1
Magnesium aspartate 4/1
Magnesium citrate 14/1
Magnesium citrate 10/1
Magnesium citrate 2/1
Magnesium gluconate
Magnesium glycerophosphate 1/1 (suggested)
Magnesium lactate 2/1
Magnesium lactate 6/1
Magnesium pidolate
Magnesium stearate 1/1
Magnesium stearate 2/1
Magnesium stearate 3/1
Malathion
Maleic acid
Malic acid 1/1
Maltitol
Manganese gluconate
Manganese glycerophosphate
Mannitol suggested
Mannitol 1/2
Maprotiline hydrochloride
Marbofloxacin
Mebendazole
Meclozine hydrochloride
Medroxyprogesterone acetate
Mefenamic acid
Mefloquine hydrochloride suggested
Megestrol acetate
Meglumine
Menadione
Menthol
Mepivacaine hydrochloride
Meprobamate
Mepyramine maleate
Mercaptopurine 1/1
Mesalazine
Mesna 1/1
Mesterolone
Mestranol
Metamizole sodium
Metformin hydrochloride
Methadone hydrochloride
Methaqualone
Methenamine
Methionine
Methotrexate suggested
Methyl nicotinate
Methyl parahydroxybenzoate
Methylatropine bromide
Methylatropine nitrate
Methyldopa 1.5/1
Methylene blue 5/1
Methylene blue 3/1
Methylene blue 4/1
Methylergometrine maleate
Methylphenobarbital
Methylprednisolone
Methylprednisolone acetate
Methylprednisolone hydrogen succinate
Methylrosanilinium chloride
Metixene hydrochloride 1/1
Metoclopramide
Metoclopramide hydrochloride 1/1
Metolazone
Metoprolol succinate
Metoprolol tartrate
Metrifonate
Metronidazole
Metronidazole benzoate 1/1
Mexiletine hydrochloride
Mianserin hydrochloride
Miconazole 1/2
Miconazole nitrate
Midazolam
Minocycline hydrochloride 2/1
Minoxidil
Mirtazapine 1/2
Misoprostol
Mitomycin 1.5/1
Mitoxantrone hydrochloride
Modafinil
Molsidomine
Mometasone furoate
Morantel hydrogen tartrate
Morphine hydrochloride 3/1
Morphine sulphate 5/1
Moxidectin
Moxifloxacin hydrochloride 1/1
Moxonidine
Mupirocin
Mupirocin calcium 2/1
N-Acetyltryptophan
N-Acetyltyrosine
Nabumetone
Nadolol
Naftidrofuryl hydrogen oxalate
Nalidixic acid
Naloxone hydrochloride 2/1
Naltrexone hydrochloride 4/1
Nandrolone decanoate
Naphazoline hydrochloride
Naphazoline nitrate
Naproxen 1.5/1
Naproxen sodium 1/1
Naproxen sodium 2/1 (polymorphic)
Naproxen sodium 4/1
Neohesperidin-dihydrochalcone 5/1
Neomycin sulphate
Neostigmine bromide
Neostigmine methylsulphate
Netilmicin sulphate
Nevirapine 1/2
Nicergoline
Niclosamide 1/1 (polymorphic)
Nicotinamide
Nicotine suggested
Nicotinic acid
Nifedipine 2/1
Niflumic acid
Nifuroxazide
Nikethamide
Nilutamide
Nimesulide
Nimodipine
Nitrazepam
Nitrendipine
Nitrofural
Nitrofurantoin 1/1 (polymorphic)
Nizatidine
Nomegestrol acetate
Noradrenaline hydrochloride suggested
Noradrenaline tartrate suggested
Norepinephrine hydrochloride suggested
Norepinephrine tartrate suggested
Norethisterone
Norethisterone acetate
Norfloxacin 2/1
Norfloxacin 1.5/1 (polymorphic)
Norfloxacin 1.25/1
Norfloxacin 2.5/1
Norfloxacin 3/1
Norfloxacin 5/1
Norgestimate
Norgestrel
Nortriptyline hydrochloride
Noscapine
Noscapine hydrochloride suggested
Nystatin
Octyl gallate 2/1
Ofloxacin
Oleic acid
Olsalazine sodium
Omeprazole
Omeprazole sodium 1/1
Ondansetron hydrochloride 2/1
Orciprenaline sulphate
Orphenadrine citrate
Orphenadrine hydrochloride
Ouabain 2/1
Ouabain 3/1
Ouabain 4/1
Ouabain 8/1
Ouabain 9/1
Ouabain 10/1
Oxacillin sodium 1/1
Oxaliplatin
Oxazepam
Oxeladin hydrogen citrate
Oxfendazole
Oxitropium bromide
Oxolinic acid
Oxprenolol hydrochloride
Oxybuprocaine hydrochloride
Oxybutynin hydrochloride
Oxycodone hydrochloride suggested
Oxymetazoline hydrochloride 1/1
Oxytetracycline 2/1
Oxytetracycline hydrochloride 1/1
Oxytetracycline hydrochloride 2/1
Oxytetracycline hydrochloride 1/2
Oxytocin
Paclitaxel 2/1
Palmitic acid
Pamidronate disodium 5/1
Pamidronate disodium 4/1
Pamidronate disodium 3/1
Pamidronate disodium 1/1
Pancuronium bromide
Pantoprazole sodium 1.5/1
Pantoprazole sodium 1/1
Pantoprazole sodium 0.5/1
Pantoprazole sodium 2/1
Papaverine hydrochloride
Paracetamol 3/1
Paracetamol 2/1
Paracetamol 1/1
Paroxetine hydrochloride 1/2
Pefloxacin mesilate 2/1
Penbutolol sulphate
Penicillamine
Pentamidine diisetionate 3/1
Pentamidine diisetionate 2/1
Pentazocine suggested
Pentazocine hydrochloride 0.23/1
Pentobarbital
Pentobarbital sodium
Pentoxifylline
Pentoxyverine hydrogen citrate
Pergolide mesilate